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ESR 09 : Bárbara Malheiros

I am a physicist and at my bachelor I had the great opportunity to spend an exchange year in the Netherlands, in the University of Groningen. During this exchange I was able to expand my knowledge and get in touch with the applied sciences world. In my master, I worked with biophysics applied to pharmaceutical sciences, studying a colloidal suspension of nanoparticle for drug delivery applications. When performing the biophysical characterization of this nanoparticles called cubosomes, I used techniques such as: X-rays scattering, electron microscopy and dynamic light scattering. In particular, I got the opportunity to learn in detail about TEM and cryo-EM during my master.

This interest for microscopy techniques brought me to the ITN network, where I will work with synthesis and characterization of particle based biosensors for medical applications, using super resolution techniques and different chemical surface DNA grafting of colloids.

Project topic: Synthesis of particles with responsive DNA ligands for super-selective biosensing

Synthesis and characterization of DNA coated colloids, via click chemistry, and  particle assembly studies. This project aims to characterize surface density and distribution. Subsequently, a fine tune of the ligands will be performed envisaging the future application in cell biosensing.

Home country

Brazil

SuperCol partner

Eindhoven University of Technology

Supervisor

Prof. Dr. Ilja Voets and Prof. Dr. Janne-Mieke Meijer

Starting date

October 2020

Publications:

None yet

Meetings:

  • SuperCol kick-off meeting, November 2020 (online)

Secondments:

  • DSM, 12-2021, 2 months
  • KUL , 06-2023, 3 months
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